| Round 1 | Team | Pick | |
| 1 | Arizona Cardinals | Kyler Murray (Oklahoma) | QB |
| 2 | San Francisco 49ers | Nick Bosa (OSU) | DE |
| 3 | New York Jets | Josh Allen (Kentucky) | EDGE |
| 4 | Oakland Raiders | Devin White (LSU) | LB |
| 5 | Tampa Bay Bucs | Montez Sweat (Miss State) | EDGE |
| 6 | New York Giants | Quinnen Williams (Alabama) | DL |
| 7 | Jacksonville Jaguars | Jawaan Taylor (Florida) | OL |
| 8 | Detroit Lions | Rashaan Gary (Michigan) | DE |
| 9 | Buffalo Bills | Ed Oliver (Houston) | DL |
| 10 | Denver Broncos | Drew Lock (Missouri) | QB |
| 11 | Cincinnati Bengals | Dwayne Haskins (Ohio St.) | QB |
| 12 | Green Bay Packers | TJ Hockenson (Iowa) | TE |
| 13 | Miami Dolphins | Clelin Ferrell (Clemson) | DE |
| 14 | Atlanta Falcons | Christian Wilkins (Clemson) | DL |
| 15 | Washington Redskins | D.K. Metcalf (Ole Miss) | WR |
| 16 | Carolina Panthers | Jonah Williams (Alabama) | OL |
| 17 | New York Giants | Brian Burns (FSU) | EDGE |
| 18 | Minnesota Vikings | Cody Ford (Oklahoma) | OL |
| 19 | Tennessee Titans | Andre Dillard (Wash St.) | OL |
| 20 | Pittsburgh Steelers | AJ Brown (Ole Miss) | WR |
| 21 | Seattle Seahawks | Byron Murphy (Washington) | CB |
| 22 | Baltimore Ravens | Devin Bush (Michigan) | LB |
| 23 | Houston Texans | Chris Lindstrom (Boston College) | OL |
| 24 | Oakland Raiders | Josh Jacobs (Alabama) | RB |
| 25 | Philadelphia Eagles | Marquise Brown (Oklahoma) | WR |
| 26 | Indianapolis Colts | Greedy Williams (LSU) | CB |
| 27 | Oakland Raiders | Dexter Lawrence (Clemson) | DL |
| 28 | L.A. Chargers | Daniel Jones (Duke) | QB |
| 29 | Kansas City Chiefs | Parrish Campbell (Ohio St.) | WR |
| 30 | Green Bay Packers | Jonathon Abram (Miss St.) | S |
| 31 | L.A. Rams | Jeffrey Simmons (Miss St.) | DL |
| 32 | New England Patriots | Noah Fant (Iowa) | TE |